Are you certain that that's an improvement?

For two options, almost certainly not ;-)

For N ports, or for a port list defined from a config file however it could be. It's even nicer in python:

    ports = [80, 443, ...]
    if port in ports and http:
        ...

Or with underscore:

    var ports = [80, 443, ...];
    if(_(ports).contains(port) && http) {
        ...
    }

Good collections make it better than manually checking the return code or checking an explicit set of port values. Also configuration > magic_nums.

If( ~[80, 443].indexOf(port) && http=== false)