Nit: One is an appetite suppressant, not a weight-loss drug. It doesn't burn fat... | Hacker News

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		irishcoffee 4 days ago \| parent \| context \| favorite \| on: U.S. had almost no job growth in 2025 Nit: One is an appetite suppressant, not a weight-loss drug. It doesn't burn fat, your body does that part. You just eat less.

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SanDiegoSun 4 days ago [–]

Incorrect, newer GLP's upregulate metabolism and increase insulin sensitivity by acting as agonists on GIP and Glucagon receptors.

Please don't comment on pharmacodynamics without a solid understanding of the underlying mechanisms.

irishcoffee 3 days ago | [–]

Which in turn regulates (suppresses) appetite.

Please don’t be a dick.

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