I've spent a lot of time thinking about this... I don't trust Drobo/Synology etc because if the unit dies I need another one to retrieve my data. Jungledisk adds up if you have 100+GB, Backblaze is the best of these services, however they are proprietary, and imagine if either were cracked and your life ended up on on a torrent server somewhere... In the end I decided upon a HP Microserver running Ubuntu with disks in RAID5 + a cheap UPS. I then have an rsync cronjob on my laptop. I tried FreeNAS but it was slow. I may consider an offsite backup of the Ubuntu server (critical files (photos etc)) to AWS with Duplicity and PGP... So far I feel the safest and happiest I've been in awhile about my backup situation.