No, they should be eliminated immediately. Finding a living mammal in the everglades is becoming rare with these snakes destroying the ecosystem. I spent several days hunting for Pythons earlier this year and didn't see even a single deer or rabbit.
We need to relieve the pressure. Pythons in the everglades have ate 90% of the mammals in the 'glades. The bigger they grow, the more they consume. While they may also eat a few other pythons, it's not a common occurrence.
If only we could make a virus or alter their DNA to wipe them out ;-)