@kwanbix: do you have kids? I feel that's one of the primary deciding factors for working from home. People without kids are much more flexible with their time, whereas people with (small) kids are severely more limited. Freeing up commute time and being able to do small chores like starting the washing machine creates significant happiness, which totally offsets the downsides of not seeing your co-workers (that) often.

Before kids I would also become depressed if I worked remotely full time. But today my "alone time" is already pretty much gone outside work hours so I don't mind being by myself during the day.