There are measures that do not depend on interpretation. Entropy of the content for instance. This is what people usually refer to in this context and the ideas of the article have actually been known to physicists for decades.
I'm out of my depth here as I've never studied information theory. I suppose there's a larger gap between the theory and the practical aspect of the title of this article than I first imagined!
Yeah, our everyday technology is maaaany orders of magnitude away from where this would be detectable. However, it is still important topic if we want to design extreme efficiency computing hardware (and already studied among researchers that want to make nanotech).
