Both the Democrats, in large part, and the Republicans, in overwhelming part, made a sort of Faustian bargain starting in the early 1970s, embracing globalization in ways that were harmful to U.S. industries but, the implied promise went, would be in the long-term best interests of the country. Partially this was economic -- a bet on trade and comparative advantage -- and partially geopolitical, in that many of the early trade deals had the effect of countering Soviet influence (e.g. Nixon's famous China trip in 1972). I think it's safe to say that not everyone felt, in the decades that followed, that they benefited as a result.
It's hard not to read this election, and particularly the Republican victories in formerly manufacturing-heavy areas like the upper Midwest and Appalachia, as a repudiation of this deal. Many people aren't impressed by either the alleged economic or geopolitical benefits of globalization, and they're expressing that extreme discontent at the ballot box.
What is the strategy for the blue collar workers? Getting rid of NAFTA and other agreements doesn't solve anything. People are getting replaced with machines and no one has come up for a solution for that.
If social safety nets get removed, they'll be in a worst position.
As others have said, this is our Brexit. The manufacturing jobs aren't coming back. The supply chains aren't here anymore. The labor is too expensive. The environmental concerns are too grave. They'll now be left with even less than they had before.
Had the media not made such a spectacle of Trump's candidacy early in the campaign, he never would have gotten anywhere near being the Republican nominee to begin with. They played chicken and lost.