This reminds me of one of my favourite flash games, Fantastic Contraption, for some reason.

For those in the UK who want a static IPv4 or IPv6 block AAISP offer a L2TP service for £2/month. It's limited to 3 megabit/s but might be enough for some use cases.

> reasonably priced storage upgrades

To be fair to Sony here, the PS5 uses a normal m.2 NVME SSD for storage upgrades.

And the ps3/ps4 before it used 2.5 inch sata drives.

Yeah, here's an example: https://play.rust-lang.org/?version=stable&mode=debug&editio...

This reminded me of this: https://www.innovationcooling.com/products/ic-diamond/?srslt... which seemed to be all the rage in PC building 10 years ago

Great work! I did something similar before with supermarket loyalty cards before Wallet support was widespread, even had the. Co-op loyalty balance on the card which updated.

I mostly read on an old iPad mini. The screen is good enough for me that I don't feel like I'm missing out by reading on a non E-ink screen.

How did you manage to get it to not bog down in speed? Every tablet I've ever had has become barely functional by year 3, and that includes the iPad Mini.

But yes, even the first gen iPad Minis were really nice screens and form-factors.

Meanwhile my Kobo Clara is just trucking along with no obvious change in battery life or responsiveness (despite the standard e-reader application processor with its power-sipping weediness).

I have a pretty old (going on eight years) iPad and it still works well enough to read an ebook. I mean, how much power do you need for that really?

Minutes to start and get the book open, and stuttering when doing things like choosing a book and turning pages was eventual my experience on all the devices: iPad Mini, Nexus 7, and a Samsung Tab 10.1. To be fair, someone else I know had an iPad Air for years and it was completely fine, so maybe they're the only tablets that actually work (or the Mini was a lemon and Androids just are bad?). Or maybe tablets are better since then: it's been a very long time since those devices went into a drawer, never to be used again.

Battery life.

It becomes very important when you are on a trip and can't easily charge your devices.

(Of course personal circumstances differ.)

It’s not the use of Uracil/Urimidine that bypasses the immune system. RNA uses Uracil instead of thymine in all organisms afaik, and RNA viruses certainly exist. It’s pseudouridine that’s the magic stuff.

This is cool, but I still see sequencing and metagenomics as being the gold standard going forward.

Metagenomics can do hard diagnoses. We achieved the first truly confirmed diagnosis of neurohistoplasmosis in our region using that technique.

Yes specifically mcfDNA which also has the advantage of only needing a blood draw

CodeCrafters has a BitTorrent client building challenge that I watched Jon Gjengset do on a stream, if someone wants to try and build their own client in an iterative and checked way.

https://app.codecrafters.io/courses/bittorrent/overview

It's worth noting that this is a paid service offering some free courses for a limited time. The BitTorrent course does not appear to be free at the moment.