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Do a speed test comparison as well. Serialization to msgpack is likely much quicker than json + gzip. This is for latency sensitive applications.


Thanks for the comparison against 23 and me but I’d be interested in how you plan to differ from Invitae/Fulgent/Myraid aside from the D2C aspects.


Great question. Right now the major difference is the D2C (patient-initiated, physician-ordered) aspect. Invitae is starting to offer this to some extent but they mainly seem focused on cardiovascular and cancer. Unlike those companies, we don't consider ourselves a testing company. For most patients in the rare disease space, understanding the underlying genetic cause is really only the first step in the process and then most need tons of help navigating the healthcare space afterwards. We started with the test, mainly because of the access and affordability issue patients were having. Many of our patients have requested tools for longitudinal phenotypic data collection, connections with all of the relevant advocacy groups, further genetic counselling, efficient ways to test family members, and detailed, patient-readable information content about their variant. We try to provide everything these patients need (aside from medical advice of course) as the healthcare system isn't currently set up to help rare disease patients.


What are some good ways to avoid distractions? I often find myself watching YouTube/Netflix or on steam for endless hours before realizing it


I find that reducing the number of decision making events by relying on a routine helps. When and where are you endlessly watching Youtube or Netflix? Is it the first thing in the morning after you grab your phone or is it happening at your desk. Depending on the answer, you want to establish a routine so you don't have to think about what you want to do next.

Let's say it's your phone first thing in the morning that is causing this problem. You could put your phone and charger far away from your bed. Then establish a sequence of actions that take you from bed to desk, without getting anywhere near your phone.

This is not an all-or-nothing method, where you fail even if you miss one step in the sequence in your routine. You start by making one or two adjustments and then build on your success.


I start a timer on my phone and run it up to ~ 8 hours to mark the end of the day. While the timer is running, I don't do anything too leisurely (e.g., playing video games). If I want/need to do something unrelated to work, I stop the timer.

The idea isn't to work exactly 8 hours per day. It's to get a sense of how much of my time is going towards work-related activities.


Check out my app: https://getcoldturkey.com


Recognizing that you cannot produce value while multi-tasking was enough for me.

You're just doing surface-level work if you're able to watch Youtube videos.


I agree consider Singapore, massive pollution problems but one of the safest countries in the world.


I got downvoted to oblivion for reporting a bug to them, with several SO devs trying to explain it’s not a bug, this doesn’t surprise me.


Europe (and HK) already have Luxembourg for that.


I assumed this meant outside the EU, similar to HK’s status compared to mainland China.


No, it’s about where money flows to avoid taxes. The comment suggested money will flow into the UK from Europe after Brexit to avoid tax, however Europe already has Luxembourg.


Isn’t Luxembourg an EU capital city? How would that help avoid EU tax?

Edit: I see you are referring to country specific taxes. Where does Hong Kong play into this then—why not just say tax haven?


No it won’t, most companies no longer offer pensions for new employees and instead offer a 401K plan. The pension problem will go away over time.


It’s positive for now, in Europe the deposit accounts are negative as well for the most part.


They're positive for regular customers, but negative for large organizations.


I still get 0,05٪ interest! That is technically positive!


What’s 0.05% minus 1.5% inflation ? Negative


The main point behind the two currency system is to prevent money laundering. You can only convert offshore to onshore via state run banks. This also has the side effect of making it easier to control import and export flow thereby inflation.

The comment below about separate interest rates has nothing to do with this discussion.


Wait you even have to physically remove it ???


Yes, like most convertible supercars/hypercars. The Pagani Huayra, all the Koenigseggs, the LaFerrari Aperta, Bugatti Veyron Grand Sport, etc.


You mean you have to use your foot to operate the gas pedal?! Man Tesla is really going downhill


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