I mean...you should always design with speed in mind (In that Jeff Dean sense :) but what 'premature optimization' is referring to, is more like localized speed optimizations/hacks. Don't do those until a) you know you'll need it and b) you know where it will help.
Ok, fellow old hacker here. I have a similar problem and I found that a lot of the hand pain was from mouse/trackpad usage. My hands have been a lot happier since going to a trackball because I don't do nearly as much gripping and pressing.
Is my remote experiences strange or do other remote workers not have some sort of chat where people ask if you've got a minute and drop in a video conference link if they need a quick chat on something?
No idea, but yes, that's exactly how we do it. We've been full remote since COVID and honestly, I don't think any of us would want it any other way but we're a very small team so not representative of larger trends.
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